Description

(3S,4R)-(3-Hydroxy-Tetrahydro-Pyran-4-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, chiral building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceuticals, particularly in the synthesis of complex molecules with defined stereochemistry. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in creating active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including protease inhibitors and other small molecule drugs.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Peptidomimetics Research: Serves as a scaffold or component in the design and synthesis of peptide analogs and mimetics for drug discovery.
• Chemical Biology Probes: Used in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	(3S,4R)-(3-Hydroxy-Tetrahydro-Pyran-4-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	2408937-23-3
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	tert-Butyl N-[(3S,4R)-3-hydroxytetrahydro-2H-pyran-4-yl]carbamate; (3S,4R)-3-Hydroxytetrahydro-2H-pyran-4-amine, N-Boc derivative; Boc-(3S,4R)-3-Hydroxy-4-aminotetrahydropyran; N-Boc-3-hydroxy-4-aminotetrahydropyran (3S,4R); (3S,4R)-4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-3-ol; 2408937-23-3; Carbamic acid, N-[(3S,4R)-3-hydroxy-4-tetrahydro-2H-pyranyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (3S,4R)-(3-Hydroxy-Tetrahydro-Pyran-4-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.