Description

4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid-D5 is a deuterium-labeled analog of a polyunsaturated fatty acid, specifically a hexadecatetraenoic acid with four cis-double bonds. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring precise and accurate analytical measurements. It is primarily required by researchers and quality control laboratories in the pharmaceutical, nutritional science, and lipidomics fields for metabolic studies, biomarker discovery, and method validation.

Application

• Mass Spectrometry Internal Standard: Critical for the accurate quantification of endogenous hexadecatetraenoic acid and related metabolites in biological samples via LC-MS/MS and GC-MS.
• Biomedical Research: Used in tracer studies to investigate lipid metabolism, inflammation pathways, and the biosynthesis of eicosanoids.
• Nutritional Science: Employed in studies analyzing the absorption, distribution, and metabolism of dietary polyunsaturated fatty acids (PUFAs).
• Pharmaceutical Development: Facilitates pharmacokinetic (PK) and pharmacodynamic (PD) studies for drug candidates targeting lipid-mediated pathways.
• Clinical Diagnostics: Serves as a reference standard in assays for lipid-based biomarkers associated with various metabolic and inflammatory diseases.
• Quality Control & Method Validation: Essential for developing and validating robust analytical methods in compliance with GLP and GMP guidelines.

Basic Information

Product Name	4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid-D5
CAS No.	2408811-79-8
Molecular Formula	C₁₆H₂₁D₅O₂
Molecular Weight	259.40 g/mol (approximate)
Synonyms	16:4(n-3)-d5; all-cis-4,7,10,13-Hexadecatetraenoic-16,16,17,17,17-d5 Acid; Hexadecatetraenoic Acid-d5; 4Z,7Z,10Z,13Z-Hexadecatetraenoic Acid-D5; Deuterated 16:4 ω-3 Fatty Acid; FA(16:4(4Z,7Z,10Z,13Z))-d5; Isotope Labeled Polyunsaturated Fatty Acid
EINECS	Contact for details

Quality Control

Every batch of 4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid-D5 is manufactured and tested to meet the stringent requirements for isotopic purity and chemical identity critical for analytical applications. Our quality assurance includes comprehensive analysis via NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for isotopic enrichment, chemical purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Chemical Purity)
Isotopic Purity (MS)	≥ 98 atom % D
Isotopic Enrichment	≥ 95% (d5)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.