Description

2-Amino-2-(2,6-Dichlorophenyl)Acetic Acid Hydrochloride is a high-purity, synthetically derived chemical building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways. It is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality raw materials for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents.
• API Synthesis: Critical building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in process development from laboratory to pilot plant and commercial manufacturing.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic research.
• Fine Chemical Synthesis: Employed in the synthesis of other specialty chemicals and advanced materials requiring a dichlorophenyl glycine derivative.

Basic Information

Product Name	2-Amino-2-(2,6-Dichlorophenyl)Acetic Acid Hydrochloride
CAS No.	2378501-46-1
Molecular Formula	C8H8Cl2NO2 • HCl
Molecular Weight	266.52 g/mol (Free base: 230.06 g/mol)
Synonyms	(2,6-Dichlorophenyl)glycine hydrochloride; 2,6-Dichloro-DL-phenylglycine hydrochloride; 2-Amino-2-(2,6-dichlorophenyl)ethanoic acid hydrochloride; α-Amino-2,6-dichlorobenzeneacetic acid hydrochloride; NSC 113928 (hydrochloride); Glycine, N-(2,6-dichlorophenyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2,6-Dichlorophenyl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.