Description

2-[(1E,3Z,5E,7E)-4-Carboxy-7-(1,3,3-Trimethyl-1,3-Dihydro-2H-Indol-2-Ylidene)-1,3,5-Heptatrien-1-Yl]-1,3,3-Trimethyl-3H-Indolium Iodide is a high-purity, functionalized polymethine dye salt, a member of the cyanine dye family, distinguished by its carboxylic acid functional group. This compound matters for its role as a key intermediate and functional chromophore in advanced material science and life sciences, where its specific photophysical properties and reactive site enable precise molecular engineering. It is primarily needed by researchers and manufacturers in the biotechnology, pharmaceutical development, and specialty chemical sectors for creating novel diagnostic agents, photosensitizers, and functional dyes.

Application

• Bioconjugation and Fluorescent Probe Synthesis: The carboxylic acid group serves as a reactive handle for covalent attachment to biomolecules (e.g., antibodies, peptides, nucleic acids) to create targeted fluorescent probes for bioimaging and diagnostics.
• Photosensitizer Development: Used in research for Photodynamic Therapy (PDT) and photoactivated drug delivery systems, leveraging its light-absorbing properties to generate reactive oxygen species.
• Functional Dye Intermediate: A critical building block for synthesizing specialized cyanine dyes with tailored solubility, spectral properties, and binding characteristics for analytical chemistry and sensor applications.
• Nonlinear Optical Materials: Investigated for use in the development of organic materials for photonics, optical data storage, and light-harvesting systems due to its extended conjugated system.
• Labeling Reagents for Flow Cytometry and Microscopy: Potential use in formulating cell-permeable stains or labels for advanced cellular analysis techniques.
• Academic and Industrial R&D: Serves as a high-value reference standard and starting material for novel chemical entity discovery in both academic and corporate research laboratories.

Basic Information

Item	Details
Product Name	2-[(1E,3Z,5E,7E)-4-Carboxy-7-(1,3,3-Trimethyl-1,3-Dihydro-2H-Indol-2-Ylidene)-1,3,5-Heptatrien-1-Yl]-1,3,3-Trimethyl-3H-Indolium Iodide
CAS No.	2311980-68-2
Molecular Formula	C31H33IN2O2
Molecular Weight	616.51 g/mol
Synonyms	Carboxycyanine dye iodide salt; 4-Carboxy-2-[7-(1,3,3-trimethylindolin-2-ylidene)hepta-1,3,5-trien-1-yl]-1,3,3-trimethyl-3H-indol-1-ium iodide; Functionalized heptamethine cyanine dye; Cy7-COOH iodide; IR-786 carboxylic acid derivative; Carboxylated indolium dye; Near-infrared cyanine acid iodide
EINECS	Contact for details

Quality Control

Our production of this high-value specialty chemical adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and spectroscopic data is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark green to blue-black crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area Percent)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.