Description

4-Octyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbaldehyde is a high-value, multi-functional organic building block that integrates a thiophene core with a formyl group and a pinacol boronate ester. This compound matters for its versatility in advanced organic synthesis, serving as a critical precursor for constructing complex molecules via cross-coupling and condensation reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for Suzuki-Miyaura cross-coupling reactions in the synthesis of drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the development of novel active ingredients for crop protection, leveraging the thiophene moiety for bioactivity.
• Organic Electronic Materials: Serves as a monomer or precursor for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Ligand and Catalyst Development: The aldehyde and boronate functional groups allow for the creation of novel bidentate ligands for metal catalysis.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex molecular libraries.
• Polymer Functionalization: Used to introduce thiophene and boronic ester functionalities into polymer backbones for specialty materials.

Basic Information

Product Name	4-Octyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbaldehyde
CAS No.	2252154-26-8
Molecular Formula	C19H31BO3S
Molecular Weight	350.33 g/mol
Synonyms	5-Formyl-4-octylthiophene-2-boronic acid pinacol ester; 2-Octyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-3-carboxaldehyde; 4-Octyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxaldehyde; Thiophene-2-carboxaldehyde, 4-octyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-octylthiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Octyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiophene-2-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.