Description

1-Trifluoromethanesulfonate is a high-purity chemical intermediate, also known as 1-Trifluoromethanesulfonate CAS NO 2251781-83-4, valued for its role as a versatile building block in advanced organic synthesis. Its unique trifluoromethanesulfonyl (triflate) group makes it a critical reagent for introducing functional complexity in target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the triflate group acts as a superior leaving group in coupling reactions.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its ability to facilitate precise molecular construction.
• Cross-Coupling Reactions: Serves as an effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) for carbon-carbon bond formation.
• Fluorination Chemistry: Acts as a precursor or reagent in pathways designed to incorporate fluorine atoms into complex organic structures.
• Laboratory Scale Process Development: Utilized in R&D for route scouting and optimization for new chemical entities.

Basic Information

Product Name	1-Trifluoromethanesulfonate
CAS No.	2251781-83-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Triflate; Trifluoromethanesulfonic acid, 1- derivative; (1-Trifluoromethanesulfonyloxy) compound; 1-OTf; 1-Trifluoromethanesulfonyl Ester; CAS 2251781-83-4
EINECS	Contact for details

Quality Control

Our 1-Trifluoromethanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.