Description

(S)-3-(2,6-Diisopropylphenyl)-1-(2-Hydroxy-1-Phenylethyl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) is a high-purity, chiral imidazolium salt primarily utilized as a sophisticated organocatalyst or chiral ligand in advanced synthetic chemistry. Its value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Organocatalysis: Employed as a chiral catalyst for enantioselective C-C bond formation, conjugate additions, and other stereospecific organic reactions.
• Pharmaceutical Intermediate Synthesis: Key reagent in the synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Ligand for Metal Complexes: Serves as a precursor for chiral N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Fine Chemical Production: Used in the manufacture of high-value, optically pure specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A critical tool for methodological development in synthetic organic chemistry within research laboratories.
• Agrochemical Synthesis: Applied in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.

Basic Information

Product Name	(S)-3-(2,6-Diisopropylphenyl)-1-(2-Hydroxy-1-Phenylethyl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V)
CAS No.	2248771-39-1
Molecular Formula	C24H33F6N2OP
Molecular Weight	510.50 g/mol
Synonyms	(S)-1-(2-Hydroxy-1-phenylethyl)-3-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; (S)-3-(2,6-Diisopropylphenyl)-1-(2-hydroxy-1-phenylethyl)-4,5-dihydro-1H-imidazol-3-ium PF6; Chiral Imidazolium Hexafluorophosphate Salt; (S)-Imidazolinium Hexafluorophosphate Catalyst; (S)-1-Phenylethanol-Substituted Imidazolinium Salt; (S)-3-(2,6-Diisopropylphenyl)-2,3-dihydro-1H-imidazol-1-ium, 1-[(1S)-2-hydroxy-1-phenylethyl]-, hexafluorophosphate(1-)
EINECS	Contact for details

Quality Control

Our production of (S)-3-(2,6-Diisopropylphenyl)-1-(2-Hydroxy-1-Phenylethyl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.