Description

(S)-3-(2,6-Diethylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) is a high-purity, chiral imidazolium salt with a hexafluorophosphate counterion, representing a sophisticated building block for advanced chemical synthesis. Its value lies in its well-defined stereochemistry and ionic character, making it a critical precursor for the development of specialized catalysts, ionic liquids, and pharmaceutical intermediates. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular control for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Catalysis: Used as a ligand or ionic component in the design of chiral catalysts for enantioselective synthesis, enhancing yield and purity of single-isomer products.
• Ionic Liquid Synthesis: Acts as a core structure for creating task-specific ionic liquids with tailored properties for green chemistry applications, separation processes, and electrolytes.
• Agrochemical Research: Employed in the development of new generation herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Material Science: Investigated for incorporation into advanced polymeric materials, conductive salts, and metal-organic frameworks (MOFs) to impart unique ionic and structural properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme mechanisms or receptor interactions due to its defined three-dimensional structure.

Basic Information

Product Name	(S)-3-(2,6-Diethylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V)
CAS No.	2248771-38-0
Molecular Formula	C18H29F6N2O2P
Molecular Weight	474.40 g/mol
Synonyms	(S)-1-(1-Hydroxy-3-methylbutan-2-yl)-3-(2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; (S)-2,6-Diethyl-N-((S)-1-hydroxy-3-methylbutan-2-yl)-N'-(2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-1-ium hexafluorophosphate; Chiral Imidazolium Hexafluorophosphate Salt; PF6 Salt of Chiral Imidazoline; (S)-Imidazolinium Hexafluorophosphate Derivative
EINECS	Contact for details

Quality Control

Our production of (S)-3-(2,6-Diethylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR spectroscopy, and precise assay determination. Certificates of Analysis (COA) documenting all critical parameters are provided to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.