Description

(4S)-7-Chloro-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride CAS NO 2241594-38-5 is a high-purity chiral building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its value lies in its defined stereochemistry and functionalized benzopyran scaffold, which is crucial for developing targeted bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry to construct complex molecules with a defined (S)-configuration at the 4-position.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Acts as a scaffold or ligand in the design of molecular probes for studying biological pathways and enzyme inhibition.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in synthetic methodology and new chemical entity discovery.

Basic Information

Product Name	(4S)-7-Chloro-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride
CAS No.	2241594-38-5
Molecular Formula	C9H11Cl2NO
Molecular Weight	220.10 g/mol
Synonyms	(4S)-7-Chloro-3,4-dihydro-2H-chromen-4-amine hydrochloride; (4S)-7-Chloro-3,4-dihydro-2H-1-benzopyran-4-amine HCl; 7-Chloro-4-aminochroman hydrochloride (S-isomer); (S)-7-Chloro-3,4-dihydro-2H-chromen-4-amine hydrochloride; (S)-7-Chloro-4-aminochroman hydrochloride; 4-Amino-7-chlorochroman hydrochloride (S-); Benzopyran-4-amine derivative
EINECS	Contact for details

Quality Control

Our (4S)-7-Chloro-3,4-Dihydro-2H-1-Benzopyran-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.