Description

(S)-tert-Butyl (1,4-Dioxan-2-Yl)Methylcarbamate is a chiral, protected amino alcohol derivative featuring a 1,4-dioxane ring, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its value lies in providing a stereochemically defined scaffold for the synthesis of complex bioactive molecules, enabling precise control over the final product's pharmacological properties. This compound is essential for R&D and production chemists in the pharmaceutical and fine chemical industries, particularly for developing novel therapeutics, chiral ligands, and catalysts.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• Chiral Auxiliary/Synthon: Used in asymmetric synthesis to induce chirality in target molecules for drug discovery programs.
• Ligand Precursor: Serves as a starting material for the development of chiral ligands used in catalytic processes.
• Peptidomimetics Research: Employed in constructing non-peptide scaffolds that mimic peptide structures for drug design.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-tert-Butyl (1,4-Dioxan-2-Yl)Methylcarbamate
CAS No.	2231663-21-9
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	tert-Butyl N-[(2S)-1,4-dioxan-2-ylmethyl]carbamate; (S)-tert-Butyl ((1,4-dioxan-2-yl)methyl)carbamate; (S)-1,4-Dioxan-2-ylmethyl-carbamic acid tert-butyl ester; (S)-N-Boc-1,4-dioxan-2-ylmethanamine; Boc-Dioxanyl-methylamine (S-isomer); (2S)-2-[(tert-Butoxycarbonylamino)methyl]-1,4-dioxane
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl (1,4-Dioxan-2-Yl)Methylcarbamate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.