Description

trans-2-(2-Isopropylphenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically valuable cyclopropane derivative used as a key chiral building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and functional group compatibility for constructing complex molecular architectures. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where its rigid cyclopropane scaffold imparts unique biological and physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and production of novel therapeutic agents, including potential antiviral, anti-inflammatory, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Employed in the development of next-generation herbicides, fungicides, and insecticides, where the cyclopropane ring can enhance metabolic stability and target specificity.
• Ligand and Catalyst Development: Used in the design and synthesis of chiral ligands and organocatalysts for asymmetric synthesis, enabling more efficient and selective chemical transformations.
• Material Science Research: Acts as a monomer or functional additive in the synthesis of specialized polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme mechanisms or protein-ligand interactions in biochemical research.

Basic Information

Product Name	trans-2-(2-Isopropylphenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	2227662-58-8
Molecular Formula	C13H16O2
Molecular Weight	204.27 g/mol
Synonyms	(1R,2S)-2-(2-Isopropylphenyl)cyclopropanecarboxylic Acid; (1S,2R)-2-(2-Isopropylphenyl)cyclopropanecarboxylic Acid; trans-2-(o-Isopropylphenyl)cyclopropanecarboxylic Acid; 2-(2-Isopropylphenyl)cyclopropanecarboxylic Acid (trans-); 2-(2-Propan-2-ylphenyl)cyclopropane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of trans-2-(2-Isopropylphenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and chiral integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports applications in GMP-aligned development and other regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.