Description

1-Bromo-3-(2-Bromoethynyl)-5-Methylbenzene is a high-purity, multi-functional brominated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both aryl bromide and bromoalkyne functionalities, makes it a versatile precursor for constructing complex molecular architectures through cross-coupling and cycloaddition reactions. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates, especially those requiring complex, halogenated aromatic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bromine atoms act as handles for further functionalization.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, via Sonogashira and other coupling reactions.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable tool for methodological studies in cross-coupling chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	1-Bromo-3-(2-Bromoethynyl)-5-Methylbenzene
CAS No.	2227272-64-0
Molecular Formula	C9H6Br2
Molecular Weight	273.95 g/mol
Synonyms	3-Bromo-5-methylphenylacetylene bromide; 1-Bromo-3-(bromoethynyl)-5-methylbenzene; 5-Methyl-1,3-dibromophenylacetylene; 2-Bromo-1-(3-bromo-5-methylphenyl)ethyne; (3-Bromo-5-methylphenyl)ethynyl bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(2-Bromoethynyl)-5-Methylbenzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.