Description

2-Bromo-9,9-Dimethyl-5-Phenyl-9H-Fluorene is a high-purity, advanced organic intermediate characterized by its brominated fluorene core with phenyl and dimethyl substituents, offering unique steric and electronic properties. This compound is critical for the synthesis of complex molecules where precise structural control and functional group compatibility are paramount. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel organic frameworks, including ligands, OLED materials, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• OLED Material Precursor: Used in the development of organic light-emitting diode (OLED) materials, where its fluorene-based structure contributes to charge transport and luminescent properties.
• Agrochemical Synthesis: Acts as an intermediate in creating advanced crop protection agents with tailored biological activity.
• Ligand Synthesis for Catalysis: Employed to construct sophisticated phosphine or nitrogen-based ligands for transition metal catalysis in asymmetric synthesis.
• Polymer & Material Science: Functions as a monomer or cross-linking agent in the production of specialty polymers with high thermal stability and specific optical characteristics.
• Academic & Industrial R&D: A valuable reagent for exploratory research in organic synthesis and the development of new functional materials.

Basic Information

Product Name	2-Bromo-9,9-Dimethyl-5-Phenyl-9H-Fluorene
CAS No.	2222970-00-3
Molecular Formula	C21H17Br
Molecular Weight	349.27 g/mol
Synonyms	2-Bromo-9,9-dimethyl-5-phenylfluorene; 9,9-Dimethyl-5-phenyl-2-bromofluorene; 5-Phenyl-2-bromo-9,9-dimethylfluorene; 2-Bromo-5-phenyl-9,9-dimethyl-9H-fluorene; 2222970-00-3; 9H-Fluorene, 2-bromo-9,9-dimethyl-5-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-9,9-Dimethyl-5-Phenyl-9H-Fluorene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.