Description

Ic-Bt-Br CAS NO 2222146-77-0 is a specialized brominated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive bromine site.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Acts as a probe or linker in bioconjugation and the development of chemical tools for biological study.
• Cross-Coupling Reactions: Functions as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Detail
Product Name	Ic-Bt-Br
CAS No.	2222146-77-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Bromo-isoquinoline-3-carboxylic acid tert-butyl ester; tert-Butyl 1-bromoisoquinoline-3-carboxylate; Ic-Bt-Br building block; 1-Bromo-3-(tert-butoxycarbonyl)isoquinoline; Isoquinoline bromo tert-butyl ester; BOC-protected bromoisoquinoline; Brominated isoquinoline derivative
EINECS	Contact for details

Quality Control

Our Ic-Bt-Br is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.