Description

1-((1S,2S)-2-(Dimethylamino)Cyclohexyl)-3-(Perfluorophenyl)Thiourea is a chiral thiourea derivative featuring a perfluorinated aromatic ring, a structure that imparts unique electronic and steric properties. This compound matters as a highly effective and selective organocatalyst and ligand precursor for asymmetric synthesis, enabling the production of enantiomerically pure intermediates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Organocatalysis: Employed as a bifunctional catalyst for enantioselective reactions such as Michael additions, Mannich reactions, and acylations.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of chiral drug candidates, particularly for constructing complex molecular architectures.
• Ligand for Metal Complexes: Serves as a precursor for chiral ligands in transition metal catalysis, enhancing selectivity in cross-coupling and hydrogenation reactions.
• Academic & Industrial R&D: A key reagent for methodological studies in organic chemistry and process chemistry optimization.
• Material Science Research: Investigated for potential applications in creating chiral surfaces or polymers with specific recognition properties.

Basic Information

Product Name	1-((1S,2S)-2-(Dimethylamino)Cyclohexyl)-3-(Perfluorophenyl)Thiourea
CAS No.	2209086-92-8
Molecular Formula	C15H16F5N3S
Molecular Weight	365.37 g/mol
Synonyms	(1S,2S)-N,N-Dimethyl-N'-(pentafluorophenyl)thiocarbamoylcyclohexane-1,2-diamine; (1S,2S)-2-(Dimethylamino)-N-(pentafluorophenyl)thiocarbamoylcyclohexanamine; Chiral Fluorinated Thiourea Catalyst; Pentafluorophenyl Thiourea Derivative; (1S,2S)-TUC; Asymmetric Thiourea Organocatalyst
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.