Description

4-Methoxy-N,2,3,6-Tetramethylbenzenesulfonamide is a specialized benzenesulfonamide derivative, a high-value synthetic intermediate prized for its role in constructing complex molecular architectures. Its core value proposition lies in providing a sterically hindered, electron-rich sulfonamide moiety, which is crucial for modulating reactivity and properties in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing new active ingredients and fine-tuning material properties in performance chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring specific pharmacokinetic profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, where the sulfonamide group can impart specific biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or as a modifying group in organometallic complexes.
• Material Science: Employed in the synthesis of advanced polymers, dyes, and photoactive materials where the methoxy and tetramethyl groups influence solubility and electronic characteristics.
• Chemical Biology Probe Synthesis: Utilized as a scaffold for creating molecular probes to study enzyme function or protein-protein interactions.

Basic Information

Product Name	4-Methoxy-N,2,3,6-Tetramethylbenzenesulfonamide
CAS No.	2197052-81-4
Molecular Formula	C12H19NO3S
Molecular Weight	257.35 g/mol
Synonyms	2,3,6-Trimethyl-4-methoxybenzenesulfonamide, N-Methylated; 4-Methoxy-2,3,6-trimethyl-N-methylbenzenesulfonamide; 2,3,6-Trimethyl-4-methoxy-N-methylbenzenesulfonamide; Benzenesulfonamide, 4-methoxy-N,2,3,6-tetramethyl-; N,2,3,6-Tetramethyl-4-methoxybenzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-Methoxy-N,2,3,6-Tetramethylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and process development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.