Description

Idt-C16-2Cho is a high-purity, synthetic lipid derivative designed for advanced research and development applications. This compound is critical for formulating next-generation lipid nanoparticles (LNPs) and other delivery systems, where its structural properties enable precise control over particle characteristics. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and advanced material scientists working on nucleic acid delivery, vaccine development, and targeted drug delivery platforms.

Application

• Lipid Nanoparticle (LNP) Formulation: A key ionizable or helper lipid component for the encapsulation and delivery of mRNA, siRNA, and other nucleic acids.
• Vaccine Development: Used in the research and production of novel vaccine delivery systems, including those for infectious diseases and oncology.
• Gene Therapy Research: Essential for creating non-viral vectors for gene editing and gene silencing applications.
• Drug Delivery Systems: Incorporated into liposomes and other nanocarriers to improve the stability, targeting, and cellular uptake of therapeutic agents.
• Biomaterial Research: Serves as a building block for synthesizing novel biomimetic membranes and functionalized surfaces.
• Diagnostic Agent Carrier: Utilized to develop contrast agents or diagnostic probes for imaging technologies.

Basic Information

Product Name	Idt-C16-2Cho
CAS No.	2177241-05-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,2-dioleoyl-3-dimethylammonium-propane (chloride salt) analog; C16 DMAP; Ionizable lipid C16; DMAP-C16; Lipidoid for LNP; (2-((2,3-bis(hexadecyloxy)propyl)dimethylammonio)ethyl) phosphate; Helper lipid for mRNA delivery
EINECS	Contact for details

Quality Control

Our Idt-C16-2Cho is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for sensitive pharmaceutical research. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.