Description

N1-(2-(4-(4-Chloro-2-Fluorophenyl)Piperazin-1-Yl)Phenyl)-N4,N4-Dimethylbenzene-1,4-Disulfonamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound is critical for the synthesis of novel therapeutic agents, particularly those targeting central nervous system (CNS) and psychiatric disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential antipsychotic and neuroleptic drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Preclinical Development: Serves as a critical material for producing batches for pharmacological and toxicological evaluation.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control in API manufacturing.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying specific receptor interactions and signaling pathways.

Basic Information

Product Name	N1-(2-(4-(4-Chloro-2-Fluorophenyl)Piperazin-1-Yl)Phenyl)-N4,N4-Dimethylbenzene-1,4-Disulfonamide
CAS No.	2171065-77-1
Molecular Formula	C24H26ClFN4O4S2
Molecular Weight	569.07 g/mol
Synonyms	4-Chloro-2-fluoro-N-[2-[4-(4-chloro-2-fluorophenyl)-1-piperazinyl]phenyl]-N',N'-dimethyl-1,4-benzenedisulfonamide; 1,4-Benzenedisulfonamide, N1-[2-[4-(4-chloro-2-fluorophenyl)-1-piperazinyl]phenyl]-N4,N4-dimethyl-; 2171065-77-1; N1-(2-(4-(4-Chloro-2-fluorophenyl)piperazin-1-yl)phenyl)-N4,N4-dimethylbenzene-1,4-disulfonamide; 4-Chloro-2-fluoro-N-(2-(4-(4-chloro-2-fluorophenyl)piperazin-1-yl)phenyl)-N',N'-dimethylbenzene-1,4-disulfonamide
EINECS	Contact for details

Quality Control

Our N1-(2-(4-(4-Chloro-2-Fluorophenyl)Piperazin-1-Yl)Phenyl)-N4,N4-Dimethylbenzene-1,4-Disulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your R&D or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.