Description

Benzyl n-[1-(Hydroxymethyl)-2-Oxabicyclo[2.1.1]Hexan-4-Yl]Carbamate is a sophisticated bicyclic carbamate derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral building block and protected intermediate, enabling the construction of complex molecular architectures with high stereochemical fidelity. Pharmaceutical and agrochemical R&D teams need it for developing novel active ingredients, particularly in the areas of medicinal chemistry and catalyst ligand design.

Application

This specialized intermediate is utilized in a variety of high-value synthetic applications, including:

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for bioactive molecules requiring rigid, oxygenated bicyclic frameworks.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides where its unique structure can impart specific biological activity and stability.
• Advanced Material Precursor: Acts as a monomer or functionalization agent in the synthesis of specialized polymers and materials with tailored properties.
• Catalyst and Ligand Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry, exploring new reaction pathways and building block utility.
• Peptidomimetics and Bioisosteres: Its structure is relevant for designing peptide mimics and bioisosteric replacements in medicinal chemistry programs.

Basic Information

Product Name	Benzyl n-[1-(Hydroxymethyl)-2-Oxabicyclo[2.1.1]Hexan-4-Yl]Carbamate
CAS No.	2170372-30-0
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	Benzyl (1-(hydroxymethyl)-2-oxabicyclo[2.1.1]hexan-4-yl)carbamate; 4-(((Benzyloxy)carbonyl)amino)-2-oxabicyclo[2.1.1]hexane-1-methanol; Carbamic acid, N-[1-(hydroxymethyl)-2-oxabicyclo[2.1.1]hex-4-yl]-, phenylmethyl ester; Bicyclo[2.1.1]hexane-1-methanol, 4-(((benzyloxy)carbonyl)amino)-2-oxa-; Benzyl N-((1s,4r)-1-(hydroxymethyl)-2-oxabicyclo[2.1.1]hexan-4-yl)carbamate (stereoisomer); Protected 2-oxabicyclo[2.1.1]hexane-4-amine derivative.
EINECS	Contact for details

Quality Control

Our production of Benzyl n-[1-(Hydroxymethyl)-2-Oxabicyclo[2.1.1]Hexan-4-Yl]Carbamate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.