Description

(S)-4-(Piperidin-3-Yl)Pyridazine is a high-purity chiral building block and pharmaceutical intermediate of significant interest in modern drug discovery. Its value lies in the rigid, nitrogen-rich bicyclic scaffold, which is highly effective for modulating biological activity and improving the pharmacokinetic properties of drug candidates. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the research and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) active drugs, kinase inhibitors, and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged piperidine-pyridazine structure.
• Ligand and Probe Synthesis: Serves as a core structure for creating chemical probes and ligands in biochemical and pharmacological assays.
• Process Chemistry & Scale-up: Employed in the development and optimization of robust synthetic routes for Active Pharmaceutical Ingredient (API) manufacturing.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis to introduce complex three-dimensional architecture into target molecules.

Basic Information

Product Name	(S)-4-(Piperidin-3-Yl)Pyridazine
CAS No.	2165925-72-2
Molecular Formula	C9H13N3
Molecular Weight	163.22 g/mol
Synonyms	(S)-3-(Pyridazin-4-yl)piperidine; (3S)-4-Pyridazin-4-ylpiperidine; (S)-4-Piperidin-3-ylpyridazine; 2165925-72-2; (S)-3-Pyridazin-4-ylpiperidine; 4-[(3S)-Piperidin-3-yl]pyridazine; (S)-4-(3-Piperidyl)pyridazine
EINECS	Contact for details

Quality Control

Every batch of (S)-4-(Piperidin-3-Yl)Pyridazine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive characterization by HPLC, GC, NMR, and MS. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for each lot, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.