Description

(S)-n-(Tetrahydro-2H-Pyran-3-Yl)Benzamide is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical manufacturers need it for creating novel therapeutic agents, particularly where stereochemistry is critical for biological activity and drug efficacy.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel small-molecule drug candidates.
• API Development: Used in research and process development for Active Pharmaceutical Ingredients requiring specific (S)-configuration.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial APIs.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(S)-n-(Tetrahydro-2H-Pyran-3-Yl)Benzamide
CAS No.	2165689-24-5
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	(S)-N-(Oxan-3-yl)benzamide; (S)-N-(Tetrahydropyran-3-yl)benzamide; Benzamide, N-[(3S)-tetrahydro-2H-pyran-3-yl]-; (S)-N-(Tetrahydro-2H-pyran-3-yl)benzamide; (3S)-N-(Tetrahydro-2H-pyran-3-yl)benzamide; (S)-Tetrahydro-2H-pyran-3-amine benzamide derivative; (S)-3-Benzamidotetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our (S)-n-(Tetrahydro-2H-Pyran-3-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.