Description

2-(4,4-Difluorooxan-3-Yl)Ethan-1-Ol is a high-purity fluorinated oxane derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluorooxane moiety, enabling precise molecular modifications that are difficult to achieve with standard intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for introducing fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated structure enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to develop specialty polymers with enhanced chemical resistance and surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and chiral molecules via reactions at the alcohol and oxane functional groups.
• Fluorine Chemistry Research: A critical reagent for studying the effects of fluorine substitution on reaction pathways and physical properties in novel compound libraries.

Basic Information

Product Name	2-(4,4-Difluorooxan-3-Yl)Ethan-1-Ol
CAS No.	2138229-45-3
Molecular Formula	C7H12F2O2
Molecular Weight	166.17 g/mol
Synonyms	2-(4,4-Difluorooxan-3-yl)ethanol; 3-(2-Hydroxyethyl)-4,4-difluorotetrahydro-2H-pyran; 4,4-Difluoro-3-(2-hydroxyethyl)tetrahydro-2H-pyran; 2-(4,4-Difluorotetrahydro-2H-pyran-3-yl)ethan-1-ol; 3-(2-Hydroxyethyl)-4,4-difluorotetrahydropyran; Difluorooxane Ethanol Derivative; CAS 2138229-45-3
EINECS	Contact for details

Quality Control

Our production of 2-(4,4-Difluorooxan-3-Yl)Ethan-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.