Description

Potassium Cyclobutylmethyltrifluoroborate is an organotrifluoroborate salt, a versatile and stable reagent widely used in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, offering superior stability and handling compared to traditional boronic acids. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for complex molecule synthesis. CAS NO 2135480-21-4.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and the cyclobutylmethyl moiety.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing the cyclobutyl group.
• Agrochemical Compound Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals.
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of structure-activity relationships (SAR) in lead optimization.
• Process Chemistry & Scale-up: Its stability makes it suitable for developing robust and scalable manufacturing routes.

Basic Information

Product Name	Potassium Cyclobutylmethyltrifluoroborate
CAS No.	2135480-21-4
Molecular Formula	C5H9BF3K
Molecular Weight	176.03 g/mol
Synonyms	Potassium (Cyclobutylmethyl)trifluoroborate; Cyclobutylmethyltrifluoroborate Potassium Salt; Potassium Cyclobutylmethanetrifluoroborate; Cyclobutylmethyl-BF3K; Potassium Trifluoro(cyclobutylmethyl)borate; K-cyclopropylmethyltrifluoroborate (common misnomer); (Cyclobutylmethyl)potassium trifluoroboranuide
EINECS	Contact for details

Quality Control

Our Potassium Cyclobutylmethyltrifluoroborate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and consistent performance in coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (NMR / HPLC)	≥95%
Water Content (KF)	≤1.0%
NMR Chemical Shift (11B)	Characteristic for trifluoroborate salts

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.