Description

2-Amino-2-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its chiral amino alcohol structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of proprietary APIs, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for enhanced bioactivity.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for high-throughput screening.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring this specialized molecular scaffold.

Basic Information

Product Name	2-Amino-2-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol Hcl
CAS No.	2135332-35-1
Molecular Formula	C9H8ClF3NO•HCl
Molecular Weight	274.52 g/mol (Free base: 237.61 g/mol)
Synonyms	2-Amino-2-(4-Chloro-3-(trifluoromethyl)phenyl)ethanol hydrochloride; 1-(4-Chloro-3-(trifluoromethyl)phenyl)-2-aminoethanol hydrochloride; 2-Amino-1-(4-chloro-3-(trifluoromethyl)phenyl)ethan-1-ol hydrochloride; (R/S)-2-Amino-2-(4-chloro-3-(trifluoromethyl)phenyl)ethanol HCl; 4-Chloro-α-(aminomethyl)-3-(trifluoromethyl)benzenemethanol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-[4-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.