Description

Pyrano[4,3-C]Pyrazole-3-Carboxylic Acid, 1,4,6,7-Tetrahydro-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those with pyrano-pyrazole core structures.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis to identify new biological leads.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target APIs under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Utilized in universities and research institutes for synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	Pyrano[4,3-C]Pyrazole-3-Carboxylic Acid, 1,4,6,7-Tetrahydro-, Methyl Ester
CAS No.	2133444-68-3
Molecular Formula	C9H10N2O3
Molecular Weight	194.19 g/mol
Synonyms	Methyl 1,4,6,7-tetrahydropyrano[4,3-c]pyrazole-3-carboxylate; 1,4,6,7-Tetrahydropyrano[4,3-c]pyrazole-3-carboxylic acid methyl ester; Pyrano[4,3-c]pyrazole-3-carboxylic acid, 1,4,6,7-tetrahydro-, methyl ester; Methyl 4,7-dihydro-1H-pyrano[4,3-c]pyrazole-3-carboxylate; CAS 2133444-68-3
EINECS	Contact for details

Quality Control

Every batch of Pyrano[4,3-C]Pyrazole-3-Carboxylic Acid, 1,4,6,7-Tetrahydro-, Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory filings and process validation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting critical parameters such as assay (HPLC), related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.