Description

(S)-(2-Methoxyphenyl)((Tetrahydro-2H-Pyran-4-Yl)Oxy)Methanol is a chiral synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of complex, biologically active molecules, enabling the creation of enantiomerically pure therapeutics. Pharmaceutical companies and advanced contract research organizations (CROs) need this high-purity intermediate to develop new drug candidates, particularly in areas requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce stereogenic centers with high enantiomeric excess.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and route scouting for efficient, cost-effective manufacturing of target drug molecules.
• Reference Standard: Utilized as an analytical standard for method development and quality control in pharmaceutical analysis.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(S)-(2-Methoxyphenyl)((Tetrahydro-2H-Pyran-4-Yl)Oxy)Methanol
CAS No.	2131091-23-9
Molecular Formula	C13H18O4
Molecular Weight	238.28 g/mol
Synonyms	(S)-2-Methoxyphenyl(tetrahydro-2H-pyran-4-yloxy)methanol; (S)-α-(2-Methoxyphenyl)-4-(tetrahydro-2H-pyran-4-yloxy)methanol; (S)-(2-Methoxyphenyl)(tetrahydropyran-4-yloxy)methanol; (S)-O-(Tetrahydro-2H-pyran-4-yl)-2-methoxybenzhydrol; (S)-Benzenemethanol, α-(2-methoxyphenyl)-4-(tetrahydro-2H-pyran-4-yloxy)-; CAS 2131091-23-9
EINECS	Contact for details

Quality Control

Our (S)-(2-Methoxyphenyl)((Tetrahydro-2H-Pyran-4-Yl)Oxy)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are supported by comprehensive analytical data, including HPLC/Chiral HPLC for purity and enantiomeric excess determination, and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.