Description

Methanesulfonic Acid, 1,1,1-Trifluoro-, 7-Phenyl-1-Dibenzofuranyl Ester is a specialized fluorinated sulfonate ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of fluorine atoms and specific aryl groups is crucial. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, materials science, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the dibenzofuran and trifluoromethanesulfonate groups can impart unique biological activity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Cross-Coupling Reactions: Functions as an effective arylating or sulfonylating agent in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl systems.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethanesulfonyl (triflyl) group, which is a powerful electron-withdrawing moiety used to modulate the electronic properties of organic molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying enzyme function or protein-protein interactions within biological systems.

Basic Information

Product Name	Methanesulfonic Acid, 1,1,1-Trifluoro-, 7-Phenyl-1-Dibenzofuranyl Ester
CAS No.	2128707-95-7
Molecular Formula	C21H13F3O4S
Molecular Weight	418.39 g/mol
Synonyms	7-Phenyl-1-dibenzofuranyl trifluoromethanesulfonate; 1-Dibenzofuran-7-ylphenyl Triflate; 7-Phenyldibenzofuran-1-yl Triflate; Trifluoromethanesulfonic Acid 7-Phenyl-1-dibenzofuranyl Ester; 7-Phenyl-1-dibenzofuranyl Triflate; 7-Phenyl-1-dibenzofuranyl Trifluoromethanesulfonate; 1-(7-Phenyldibenzofuran-1-yl) Triflate
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as NMR (¹H, ¹³C, ¹⁹F), HPLC, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.