Description

p-Nh-Bn-Oxo-Do3A is a high-purity, bifunctional chelating agent and chemical intermediate, specifically designed for advanced conjugation chemistry. Its core value lies in its ability to form exceptionally stable complexes with various metal ions, making it a critical component in the development of targeted diagnostic and therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and medical imaging sectors who require reliable, high-quality building blocks for innovative radiopharmaceuticals and contrast agents.

Application

• Radiopharmaceutical Precursor: Key intermediate for synthesizing ligands used in Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) imaging agents.
• Contrast Agent Development: Chelator for gadolinium and other lanthanides in the research and production of next-generation Magnetic Resonance Imaging (MRI) contrast media.
• Targeted Drug Conjugation: Enables the stable attachment of cytotoxic payloads or imaging isotopes to antibodies, peptides, and other targeting molecules for targeted cancer therapies (e.g., antibody-drug conjugates, radiotheranostics).
• Research Chemical: Used in academic and industrial R&D for studying metal-ligand interactions, developing new chelation platforms, and exploring novel diagnostic applications.
• Bioconjugation Tool: Serves as a versatile linker molecule for attaching functional groups to biomolecules in assay development and diagnostic kit manufacturing.

Basic Information

Product Name	p-Nh-Bn-Oxo-Do3A
CAS No.	2125661-90-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 10-(4-aminobenzyl)-1-oxo-; 10-(4-Aminobenzyl)-1-oxo-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid; p-Aminobenzyl-Oxo-DO3A; NH2-Bn-Oxo-DO3A; Oxo-DO3A-p-aminobenzyl; Bifunctional DO3A chelator; p-NH2-Bn-Oxo-DO3A; Aminobenzyl-DO3A derivative
EINECS	Contact for details

Quality Control

Our p-Nh-Bn-Oxo-Do3A is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.