Description

5-Cyclopropyl-2-Fluoropyridine-3-Boronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a key Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to create novel heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biological target identification and validation.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry approaches.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	5-Cyclopropyl-2-Fluoropyridine-3-Boronic Acid
CAS No.	2121511-59-7
Molecular Formula	C8H9BFNO2
Molecular Weight	180.97 g/mol
Synonyms	(5-Cyclopropyl-2-fluoropyridin-3-yl)boronic acid; 2-Fluoro-5-cyclopropylpyridine-3-boronic acid; 3-Borono-5-cyclopropyl-2-fluoropyridine; 5-Cyclopropyl-2-fluoro-3-pyridineboronic acid; Boronic acid, B-(5-cyclopropyl-2-fluoro-3-pyridinyl)-; 2121511-59-7; 5-Cyclopropyl-2-fluoropyridine-3-boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 5-Cyclopropyl-2-Fluoropyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.