Description

5-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its chiral pyran ring structure, which serves as a key scaffold in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis due to its defined stereochemistry.
• Academic & Contract Research: Supplied to universities and CROs for fundamental organic synthesis research and custom synthesis projects.

Basic Information

Product Name	5-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride
CAS No.	2102408-50-2
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	5-Amino-3-hydroxytetrahydro-2H-pyran hydrochloride; 3-Hydroxy-5-aminotetrahydropyran HCl; 5-Amino-3-hydroxytetrahydropyran hydrochloride; Tetrahydro-2H-pyran-3-ol, 5-amino-, hydrochloride; 5-Aminotetrahydro-2H-pyran-3-ol HCl; (3R,5S)-5-Aminotetrahydro-2H-pyran-3-ol hydrochloride (if stereospecific); (3S,5R)-5-Aminotetrahydro-2H-pyran-3-ol hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aminotetrahydro-2H-Pyran-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.