Description

2H-Pyran, 4-[(1R)-2-Bromo-1-(2-Methoxyphenyl)Ethoxy]Tetrahydro- is a high-purity, chiral synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its complex molecular architecture, featuring a tetrahydro-2H-pyran ring and a brominated ethoxy side chain attached to a methoxyphenyl group, which makes it a versatile building block for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Asymmetric Synthesis: Utilized as a key reagent in stereoselective reactions to introduce specific chiral centers into complex organic molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Fine Chemical Production: Acts as a specialized building block for the manufacture of high-value, low-volume chemicals used in agrochemicals and material science.
• Academic & Contract Research: Used in university laboratories and CROs (Contract Research Organizations) for methodological development and exploratory synthesis.

Basic Information

Product Name	2H-Pyran, 4-[(1R)-2-Bromo-1-(2-Methoxyphenyl)Ethoxy]Tetrahydro-
CAS No.	2098543-62-3
Molecular Formula	C14H19BrO3
Molecular Weight	315.20 g/mol
Synonyms	4-[(1R)-2-Bromo-1-(2-Methoxyphenyl)Ethoxy]Tetrahydro-2H-Pyran; (R)-4-(2-Bromo-1-(2-Methoxyphenyl)Ethoxy)Tetrahydro-2H-Pyran; Tetrahydro-2H-pyran-4-yl (1R)-2-bromo-1-(2-methoxyphenyl)ethyl ether; Brominated Chiral Pyran Ether Intermediate; 2098543-62-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. We adhere to strict Good Manufacturing Practice (GMP) principles for high-value intermediates, with quality assurance protocols designed to meet the exacting requirements of pharmaceutical R&D. Each batch is characterized to confirm identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for materials soluble in strong acid/organic solvent. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.