Description

3-(4-Bromophenyl)-2,2-Difluorocyclopropane-1-Carboxylic Acid is a high-purity fluorinated cyclopropane carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the difluorocyclopropane ring, which is highly sought after for constructing complex molecular architectures with enhanced properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An important substrate for studying the effects of fluorinated cyclopropanes on molecular conformation and biological activity.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step synthetic routes for client-specific molecules.

Basic Information

Product Name	3-(4-Bromophenyl)-2,2-Difluorocyclopropane-1-Carboxylic Acid
CAS No.	2098048-73-6
Molecular Formula	C10H7BrF2O2
Molecular Weight	277.06 g/mol
Synonyms	2,2-Difluoro-3-(4-bromophenyl)cyclopropanecarboxylic Acid; 3-(p-Bromophenyl)-2,2-difluorocyclopropane-1-carboxylic Acid; 4-Bromo-α,α-difluorocyclopropaneacetic Acid; (1R,3S)-3-(4-Bromophenyl)-2,2-difluorocyclopropanecarboxylic Acid (enantiomer); (1S,3R)-3-(4-Bromophenyl)-2,2-difluorocyclopropanecarboxylic Acid (enantiomer); Difluorocyclopropane Carboxylic Acid Bromophenyl Derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-2,2-Difluorocyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.