Description

3-Nitro-4-(Trifluoromethoxy)Phenyl)-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block, essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction. Its core value lies in enabling the efficient and selective introduction of the substituted phenyl ring into complex molecular architectures, which is critical for pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring the 3-nitro-4-(trifluoromethoxy)phenyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where its specific aromatic structure can tune electronic properties.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and drug discovery targets.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	3-Nitro-4-(Trifluoromethoxy)Phenyl)-Boronic Acid Pinacol Ester
CAS No.	2096336-45-5
Molecular Formula	C₁₃H₁₅BF₃NO₅
Molecular Weight	333.07 g/mol
Synonyms	4-(Trifluoromethoxy)-3-nitrophenylboronic acid pinacol ester; (3-Nitro-4-(trifluoromethoxy)phenyl)boronic acid pinacol ester; 2-[3-Nitro-4-(trifluoromethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Nitro-4-trifluoromethoxyphenylboronic acid pinacol ester; Boronic acid, B-[3-nitro-4-(trifluoromethoxy)phenyl]-, 1,1-dimethylethyl ester (9CI); PINACOL 3-NITRO-4-(TRIFLUOROMETHOXY)BENZENEBORONATE
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(Trifluoromethoxy)Phenyl)-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.