Description

Potassium (3-(tert-Butoxycarbonyl)-3-Azabicyclo[4.1.0]Heptan-6-Yl)Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its exceptional stability and reactivity as a coupling partner in transition-metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, enabling the efficient and precise construction of complex molecular architectures. Its protected amine functionality offers strategic advantages for multi-step synthesis.

Application

• As a key boronic acid equivalent in Suzuki-Miyaura cross-coupling reactions for C-C bond formation.
• Advanced intermediate in the synthesis of pharmaceutical active ingredients (APIs) and drug candidates, particularly those containing complex, strained ring systems.
• Building block for agrochemicals and fine chemicals requiring specific, sterically defined bicyclic structures.
• Precursor in medicinal chemistry for creating focused libraries of compounds for biological screening.
• Used in material science research for the development of novel organic molecules with specific electronic properties.
• Intermediate in asymmetric synthesis and the preparation of chiral ligands or catalysts.

Basic Information

Product Name	Potassium (3-(tert-Butoxycarbonyl)-3-Azabicyclo[4.1.0]Heptan-6-Yl)Trifluoroborate
CAS No.	2095504-46-2
Molecular Formula	C11H16BF3KNO2
Molecular Weight	289.16 g/mol
Synonyms	Potassium (3-(Boc)-3-azabicyclo[4.1.0]heptan-6-yl)trifluoroborate; 3-(tert-Butoxycarbonyl)-3-azabicyclo[4.1.0]heptan-6-yltrifluoroborate potassium salt; 6-Trifluoroboratomethyl-3-azabicyclo[4.1.0]heptane-3-carboxylic acid tert-butyl ester potassium salt; Potassium Trifluoro((1R,6S)-3-((tert-butoxycarbonyl)-3-azabicyclo[4.1.0]heptan-6-yl)borate; Boc-3-Aza-bicyclo[4.1.0]heptane-6-trifluoroborate potassium; (1S,6R)-3-[(tert-Butoxycarbonyl)-3-azabicyclo[4.1.0]hept-6-yl]trifluoroborate potassium
EINECS	Contact for details

Quality Control

Our Potassium (3-(tert-Butoxycarbonyl)-3-Azabicyclo[4.1.0]Heptan-6-Yl)Trifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator for long-term stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
1H NMR Purity	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.