Description

2H-Pyran, 2-(4-Bromophenyl)-5-Ethyltetrahydro-, (2R,5S)-Rel- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromophenyl and tetrahydropyran motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, including potential CNS-active compounds.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide candidates, leveraging the bromophenyl moiety for further functionalization.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers or functionalized polymers with tailored properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological systems and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.

Basic Information

Product Name	2H-Pyran, 2-(4-Bromophenyl)-5-Ethyltetrahydro-, (2R,5S)-Rel-
CAS No.	2092925-71-6
Molecular Formula	C13H17BrO
Molecular Weight	269.18 g/mol
Synonyms	rel-(2R,5S)-2-(4-Bromophenyl)-5-ethyltetrahydro-2H-pyran; 5-Ethyl-2-(4-bromophenyl)tetrahydro-2H-pyran; (2R,5S)-2-(4-Bromophenyl)-5-ethyltetrahydro-2H-pyran (relative); 2-(p-Bromophenyl)-5-ethyltetrahydropyran; Bromophenyl ethyl tetrahydropyran; BPhETHP; CAS 2092925-71-6
EINECS	Contact for details

Quality Control

Our 2H-Pyran, 2-(4-Bromophenyl)-5-Ethyltetrahydro-, (2R,5S)-Rel- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric/excess, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for use in regulated research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and oxidation; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (rel-(2R,5S))
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.