Description

trans-2-Methyl-Tetrahydro-Pyran-4-Ylamine is a versatile chiral amine building block featuring a tetrahydro-2H-pyran scaffold. This compound is valued for its rigid, oxygen-containing heterocyclic structure, which can impart favorable pharmacokinetic properties in active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, asymmetric synthesis, and as a key intermediate in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pyran moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and other enantioselective transformations.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	trans-2-Methyl-Tetrahydro-Pyran-4-Ylamine
CAS No.	2091286-52-9
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	trans-4-Amino-2-methyltetrahydro-2H-pyran; (4R*,6S*)-6-Methyltetrahydro-2H-pyran-4-amine; 2-Methyltetrahydropyran-4-amine (trans); 4-Amino-2-methyltetrahydropyran; trans-2-Methyl-4-aminotetrahydropyran; 2-Methyl-4-aminotetrahydropyran, trans-; Tetrahydro-2-methyl-4-pyranamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of trans-2-Methyl-Tetrahydro-Pyran-4-Ylamine is analyzed to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as assay (by GC or HPLC), enantiomeric excess (by chiral HPLC), and impurity profiles are available upon request. We adhere to cGMP principles for pharmaceutical-grade intermediates to ensure supply chain reliability and product consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.