Description

(4R,5S,6S)-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2,5-Diol is a high-purity, chiral pyran derivative with significant synthetic utility. This compound serves as a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile chiral building block for complex organic synthesis. It is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high stereochemical purity for developing active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of novel drug candidates, especially in antibiotic and antiviral research.
• Chiral Building Block: Used in asymmetric synthesis to construct complex molecules with defined stereocenters for medicinal chemistry.
• Agrochemical Research: Intermediate in the development of new, stereoselective pesticides and herbicides.
• Fine Chemical Synthesis: Precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and catalysis.
• Process Chemistry: Used in scale-up and route development for the commercial production of chiral molecules.

Basic Information

Product Name	(4R,5S,6S)-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2,5-Diol
CAS No.	2089577-97-7
Molecular Formula	C8H16O5
Molecular Weight	192.21 g/mol
Synonyms	4-Methoxy-4,6-dimethyltetrahydro-2H-pyran-2,5-diol (4R,5S,6S)-; (4R,5S,6S)-4-Methoxy-4,6-dimethyltetrahydropyran-2,5-diol; (4R,5S,6S)-4,6-Dimethyl-4-methoxytetrahydro-2H-pyran-2,5-diol; Chiral Pyran Diol Derivative; 4-Methoxy-4,6-dimethyltetrahydropyran-2,5-diol; 2089577-97-7; (4R,5S,6S)-isomer of 4-Methoxy-4,6-dimethyltetrahydro-2H-pyran-2,5-diol
EINECS	Contact for details

Quality Control

Our (4R,5S,6S)-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2,5-Diol is manufactured under strict quality control protocols to ensure high chemical and stereochemical purity. Each batch is analyzed using advanced techniques including HPLC, GC, and chiral analysis to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor quality systems to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (4R,5S,6S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.