Description

1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one is a high-value, synthetically challenging bicyclic ketone derivative. This compound matters as a sophisticated chemical building block for advanced research and development in medicinal chemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used as a rigid, three-dimensional core structure in fragment-based drug discovery and lead optimization programs.
• Agrochemical Synthesis: Serves as a precursor for novel crop protection agents requiring unique steric and electronic properties.
• Material Science: Potential monomer or cross-linking agent for creating polymers with specific thermal or mechanical characteristics.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in organic synthesis and catalysis.
• Custom Synthesis & Scale-up: A target molecule for process chemistry development and cGMP manufacturing for clinical trial materials.

Basic Information

Product Name	1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one
CAS No.	2055839-77-3
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	1-(3-Hydroxybicyclo[1.1.1]pentan-1-yl)ethanone; 1-Acetyl-3-hydroxybicyclo[1.1.1]pentane; 3-Hydroxybicyclo[1.1.1]pentane-1-acetic acid ketone; 3-Hydroxy-1-acetylbicyclo[1.1.1]pentane; Bicyclo[1.1.1]pentan-1-one, 3-hydroxy-1-acetyl derivative; [1.1.1]Propellane ketone derivative
EINECS	Contact for details

Quality Control

Our 1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are available upon request. We support development from milligram to kilogram scale with reliable documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.