Description

3-Bromo-4-(2,4-Difluorophenoxy)Aniline Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aniline structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals. The product is supplied with full analytical documentation to ensure batch-to-batch consistency and support rigorous R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its difluorophenoxy moiety for bioactivity.
• Material Science: Acts as a monomer or precursor in the creation of specialized polymers and liquid crystals for electronic displays.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for other functionalized aniline derivatives in academic and industrial labs.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing complex, halogenated dyes and pigments with enhanced lightfastness and color properties.

Basic Information

Item	Details
Product Name	3-Bromo-4-(2,4-Difluorophenoxy)Aniline Hydrochloride
CAS No.	2007921-24-4
Molecular Formula	C12H9BrClF2NO
Molecular Weight	336.56 g/mol
Synonyms	3-Bromo-4-(2,4-difluorophenoxy)benzenamine hydrochloride; 4-Amino-2-bromo-1-(2,4-difluorophenoxy)benzene hydrochloride; 2,4-Difluoro-1-[(3-bromo-4-aminophenyl)oxy]benzene hydrochloride; 3-Bromo-4-(2,4-difluorophenoxy)phenylamine HCl; 3-Br-4-(2,4-F2PhO)C6H3NH2·HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(2,4-Difluorophenoxy)Aniline Hydrochloride is manufactured under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.