Description

2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3S)- is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized pyran ring structure, which serves as a key intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the specific stereochemistry can influence biological activity and environmental profile.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance molecules, flavors, and other specialty fine chemicals requiring high stereochemical purity.
• Academic & Institutional Research: A valuable tool for synthetic methodology development and exploring structure-activity relationships (SAR) in medicinal chemistry programs.
• Peptidomimetics & Bioisosteres: The tetrahydro-2H-pyran scaffold is used as a bioisostere for sugar or other ring systems in drug design, making this amine a key building block.

Basic Information

Product Name	2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3S)-
CAS No.	2007916-42-7
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	(3S)-Tetrahydro-2H-pyran-3-methanamine hydrochloride; (3S)-3-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (S)-3-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (S)-Tetrahydro-2H-pyran-3-ylmethanamine hydrochloride; (3S)-3-(Aminomethyl)oxane hydrochloride; (S)-Oxan-3-ylmethanamine hydrochloride; Tetrahydro-2H-pyran-3-methanamine, (3S)-, hydrochloride; A chiral tetrahydro-2H-pyran-3-methylamine HCl salt.
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.