Description

2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3R)- is a high-purity chiral amine derivative, specifically the hydrochloride salt of the (3R)-enantiomer of tetrahydro-2H-pyran-3-methanamine. This compound is a valuable chiral building block and intermediate in modern synthetic organic chemistry, prized for its defined stereochemistry which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis.
• Academic and R&D Laboratories: Employed in medicinal chemistry programs and process research for route scouting and optimization.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3R)-
CAS No.	2007916-32-5
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	(3R)-Tetrahydro-2H-pyran-3-methanamine hydrochloride; (R)-Tetrahydro-2H-pyran-3-methanamine HCl; (3R)-3-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (R)-3-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (R)-THPMA-HCl; (R)-Aminomethyltetrahydropyran hydrochloride; (3R)-Tetrahydro-2H-pyran-3-ylmethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2H-Pyran-3-Methanamine, Tetrahydro-, Hydrochloride (1:1), (3R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.