Description

(-)-Egcg-4'-o-Me is a specific methylated derivative of the well-known catechin, (-)-Epigallocatechin gallate (EGCG). This compound is valued for its enhanced metabolic stability and bioavailability compared to its parent molecule, making it a critical compound for advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and life science industries for applications in metabolic studies, anti-inflammatory research, and as a high-purity reference standard.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery and development.
• Nutraceutical R&D: Serves as a key intermediate or active ingredient in research for developing advanced dietary supplements targeting metabolic health and oxidative stress.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate mechanisms related to cell signaling, inflammation, and cancer pathways.
• Cosmeceutical Applications: Investigated for potential use in premium skincare formulations for its antioxidant and protective properties.
• Academic Research: Utilized in universities and research institutes for pharmacological and chemical studies on flavonoid derivatives.

Basic Information

Item	Details
Product Name	(-)-Egcg-4'-o-Me
CAS No.	298700-57-9
Molecular Formula	C23H20O11
Molecular Weight	472.40 g/mol
Synonyms	(-)-Epigallocatechin 4'-O-methyl gallate; 4'-O-Methyl-(-)-epigallocatechin gallate; 4'-O-Methyl EGCG; EGCG 4'-methyl ether; 3-O-Galloyl-4'-O-methyl-(-)-epigallocatechin; Methylated EGCG; 4'-Methoxy EGCG
EINECS	Contact for details

Quality Control

Our (-)-Egcg-4'-o-Me is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. For short-term use, store at 2-8°C. The material is easily oxidized and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.