Description

3-Pyridazinemethanol, 5-Aminohexahydro-4-Hydroxy-, (3R,4S,5R)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the research and development of novel pharmaceutical agents, particularly those targeting complex biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate sophisticated, functionalized pyridazine motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of potential active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that utilize the pyridazine scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Fine Chemical Synthesis: Utilized in multi-step synthetic routes to construct complex natural product analogs or other high-value specialty chemicals.
• Academic & Institutional Research: A valuable compound for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Pyridazinemethanol, 5-Aminohexahydro-4-Hydroxy-, (3R,4S,5R)- (9Ci)
CAS No.	296784-04-8
Molecular Formula	C7H15N3O2
Molecular Weight	173.21 g/mol
Synonyms	(3R,4S,5R)-5-Aminohexahydro-4-hydroxy-3-pyridazinemethanol; 5-Aminohexahydro-4-hydroxy-3-pyridazinemethanol (3R,4S,5R)-; Hexahydro-5-amino-4-hydroxy-3-pyridazinemethanol, (3R,4S,5R)-; (3R,4S,5R)-5-Amino-4-hydroxyhexahydro-3-pyridazinemethanol; 3-Pyridazinemethanol, 5-aminohexahydro-4-hydroxy-, (3R,4S,5R)-; (3R,4S,5R)-5-Amino-4-hydroxypiperidine-3-methanol (tautomeric form); A chiral amino-hydroxypyridazine derivative.
EINECS	Contact for details

Quality Control

Our 3-Pyridazinemethanol, 5-Aminohexahydro-4-Hydroxy-, (3R,4S,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.