Description

2-Benzyloxymethyl-Cyclobutanone is a specialized organic building block featuring a cyclobutanone core functionalized with a benzyloxymethyl side chain. This compound matters as a versatile chiral synthon, enabling the synthesis of complex molecules with precise stereochemistry for advanced research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its functionalized cyclobutane ring.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Material Science: Potential monomer or cross-linking agent for creating polymers with unique thermal or mechanical properties derived from the strained cyclobutanone ring.
• Academic & Industrial R&D: Employed in methodological chemistry research for ring-expansion reactions, [2+2] cycloaddition studies, and other cyclobutane chemistry.
• Flavor & Fragrance Industry: Intermediate for the synthesis of complex musks and other fragrance molecules where the cyclobutanone structure imparts specific olfactory characteristics.

Basic Information

Item	Details
Product Name	2-Benzyloxymethyl-Cyclobutanone
CAS No.	294868-56-7
Molecular Formula	C13H16O2
Molecular Weight	204.26 g/mol
Synonyms	2-(Benzyloxymethyl)cyclobutanone; (Oxymethylene)benzene Cyclobutanone Derivative; 2-(Phenylmethoxymethyl)cyclobutanone; BOM-Cyclobutanone; α-(Benzyloxymethyl)cyclobutanone; Cyclobutanone, 2-(benzyloxymethyl)-; 294868-56-7; Benzyloxymethyl cyclobutanone
EINECS	Contact for details

Quality Control

Every batch of 2-Benzyloxymethyl-Cyclobutanone is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.