Description

2-Bromo-1-Methyl-Cyclopropanecarboxylic Acid is a versatile and high-value cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its unique sterically constrained structure makes it an essential intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is particularly valuable for pharmaceutical research and development, agrochemical synthesis, and the creation of novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring cyclopropane rings for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropane moiety enhances efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis and R&D: Supplied to contract research organizations (CROs) and fine chemical companies for custom synthesis projects and library development.

Basic Information

Product Name	2-Bromo-1-Methyl-Cyclopropanecarboxylic Acid
CAS No.	292623-33-7
Molecular Formula	C5H7BrO2
Molecular Weight	179.01 g/mol
Synonyms	1-Methyl-2-bromocyclopropanecarboxylic acid; 2-Bromo-1-methylcyclopropanecarboxylic acid; 2-Bromo-1-methyl-1-cyclopropanecarboxylic acid; (1-Methyl-2-bromocyclopropyl)formic acid; Bromomethylcyclopropanecarboxylic acid; α-Bromo-β-methylcyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-Methyl-Cyclopropanecarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.