Description

2-Bromo-4-Ethyl-1-Iodobenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and iodine atoms on the ethylbenzene ring, which allows for sequential, site-selective cross-coupling reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring selective aryl-aryl bond formation via Suzuki, Stille, or Negishi coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the ethyl and halogen substituents can be leveraged to fine-tune biological activity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands for transition metal catalysts used in homogeneous catalysis.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its halogenated structure allows for functionalization and polymerization.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems due to the reactivity of the iodine atom in bioconjugation chemistry.

Basic Information

Product Name	2-Bromo-4-Ethyl-1-Iodobenzene
CAS No.	289039-23-2
Molecular Formula	C8H8BrI
Molecular Weight	310.96 g/mol
Synonyms	1-Bromo-2-ethyl-4-iodobenzene; 4-Ethyl-2-bromo-1-iodobenzene; 2-Bromo-4-ethyl-1-iodobenzene; 2-Bromo-4-ethyl-1-iodobenzene, 97%; 1-Iodo-2-bromo-4-ethylbenzene; Benzene, 2-bromo-4-ethyl-1-iodo-; (2-Bromo-4-ethylphenyl)iodide
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Ethyl-1-Iodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality ensures material consistency, which is critical for your research and process development success.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.