Description

3-Bromo-4,5-Diiodotoluene is a halogenated aromatic compound of significant interest in advanced organic synthesis. This multi-halogenated toluene derivative serves as a versatile and valuable building block for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications requiring precise halogen substitution patterns.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores for bioactivity or as synthetic handles for further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific bromine and iodine atoms contribute to the compound's binding affinity and stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating halogenated organic semiconductors and liquid crystal molecules, where heavy halogens can influence electronic properties and molecular alignment.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of both bromine and iodine, which have different reactivity profiles, allowing for sequential, selective functionalization.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) or homogeneous catalysis, where the halogenated aromatic system can be further modified.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	3-Bromo-4,5-Diiodotoluene
CAS No.	289038-08-0
Molecular Formula	C7H5BrI2
Molecular Weight	438.83 g/mol
Synonyms	1-Bromo-2,3-diiodo-4-methylbenzene; 3-Bromo-4,5-diiodo-1-methylbenzene; Toluene, 3-bromo-4,5-diiodo-; 4-Methyl-3-bromo-1,2-diiodobenzene; 2,3-Diiodo-4-methylbromobenzene; 3-Bromo-4,5-diiodotoluol
EINECS	Contact for details

Quality Control

Our 3-Bromo-4,5-Diiodotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.