Description

(n-(3-Trifluoromethyl)Benzenesulfonyl)Alanine CAS NO 288266-54-6 is a specialized organofluorine building block featuring a sulfonamide-linked alanine moiety. This compound is valued for its role in medicinal chemistry and agrochemical research, where the trifluoromethyl and benzenesulfonyl groups confer unique physicochemical properties. It is primarily utilized by research scientists and process chemists in the pharmaceutical and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of protease inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides and pesticides, leveraging the biological activity of the sulfonamide and trifluoromethyl groups.
• Peptidomimetics: Serves as a constrained amino acid analog in the design of peptide-like compounds with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the creation of activity-based probes and labeled compounds for studying enzyme function.
• Material Science: Potential monomer or additive for specialty polymers where fluorine content is desired for surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	(n-(3-Trifluoromethyl)Benzenesulfonyl)Alanine
CAS No.	288266-54-6
Molecular Formula	C10H10F3NO4S
Molecular Weight	297.25 g/mol
Synonyms	N-[(3-Trifluoromethyl)phenyl]sulfonylalanine; 2-[[(3-Trifluoromethyl)phenyl]sulfonylamino]propanoic acid; 3-(Trifluoromethyl)benzenesulfonylalanine; Alanine, N-[(3-trifluoromethyl)benzenesulfonyl]-; (3-Trifluoromethylbenzenesulfonyl)alanine; TFMBS-Alanine; 288266-54-6 (CAS)
EINECS	Contact for details

Quality Control

Our (n-(3-Trifluoromethyl)Benzenesulfonyl)Alanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.