Description

3-Hexen-2-One, 5-Hydroxy-, (3E,5S)- (9Ci) is a chiral, unsaturated hydroxy ketone with a defined stereochemistry, making it a valuable building block in fine chemical synthesis. Its specific (3E,5S) configuration is critical for applications requiring high stereochemical purity, such as in the production of advanced pharmaceutical intermediates and chiral ligands. This compound is sought after by R&D and production teams in the pharmaceutical, agrochemical, and flavor & fragrance industries for its role in creating complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring specific enantiomeric control.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the stereochemistry influences biological activity.
• Flavor and Fragrance Ingredient: Serves as a precursor for creating specific green, fruity, or herbal aroma compounds due to its unsaturated carbonyl structure.
• Chemical Research: Employed in academic and industrial laboratories as a model compound for studying asymmetric synthesis, catalysis, and reaction mechanisms.
• Ligand and Catalyst Development: The hydroxy and ketone functional groups make it a useful scaffold for designing new chiral ligands and organocatalysts.

Basic Information

Product Name	3-Hexen-2-One, 5-Hydroxy-, (3E,5S)- (9Ci)
CAS No.	288153-65-1
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(3E,5S)-5-Hydroxy-3-hexen-2-one; (5S,3E)-5-Hydroxy-3-hexen-2-one; (S,E)-5-Hydroxy-3-hexen-2-one; 3-Hexen-2-one, 5-hydroxy-, (3E,5S)-; 5-Hydroxy-3-hexen-2-one (3E,5S)-; Chiral 5-hydroxy-3-hexen-2-one; (E)-(5S)-5-Hydroxy-3-hexen-2-one
EINECS	Contact for details

Quality Control

Our 3-Hexen-2-One, 5-Hydroxy-, (3E,5S)- (9Ci) is produced under strict quality management systems. Each batch is characterized and tested to ensure high chiral purity and chemical identity, with critical parameters including enantiomeric excess (ee) and chemical purity assessed by advanced analytical techniques. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment to guarantee traceability and compliance with your research or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.