Description

n-Hydroxy-3-Phenyl-Propionamidine is a specialized amidine derivative with a hydroxamic acid-like functional group, offering unique chelating and nucleophilic properties. This compound is valued as a versatile chemical intermediate and pharmacological research tool, particularly in the development of enzyme inhibitors and metal-chelating agents. It is primarily required by pharmaceutical R&D laboratories, fine chemical synthesis units, and academic institutions focused on medicinal chemistry and bioinorganic studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting metalloenzymes like matrix metalloproteinases (MMPs).
• Research Chemical: Used in biochemical and pharmacological research as a potential inhibitor for arginase and other amidine-/guanidine-processing enzymes.
• Chelating Agent Precursor: Serves as a starting material for synthesizing specialized ligands used in metal catalysis and separation processes.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the N-hydroxyamidine moiety into more complex molecular architectures.
• Agrochemical Research: Investigated for the development of new plant growth regulators or pesticides due to its bioactive structure.

Basic Information

Product Name	n-Hydroxy-3-Phenyl-Propionamidine
CAS No.	287963-68-2
Molecular Formula	C9H12N2O
Molecular Weight	164.21 g/mol
Synonyms	3-Phenylpropionhydroxamic amidine; N-Hydroxy-3-phenylpropionamidine; 3-Phenyl-N-hydroxypropionamidine; Benzenepropanamidine, N-hydroxy-; Hydroxy-3-phenyl-propionamidine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-3-Phenyl-Propionamidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and we support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.